
产品货号:
Z11963
中文名称:
BID抗体
英文名称:
Anti-BID Antibody
产品规格:
0.1mg
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-BID Antibody |
指标别名 | BID;FP497;p11 BID;p22 BID |
克隆性 | Polyclonal |
检验物种 | human,mouse |
应用范围 | ELISA,WB,IHC,IF |
基因名称 | BID |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Bid antibody was raised against a peptide corresponding to 14 amino acids near the carboxy terminus of human Bid.The immunogen is located within amino acids 120 - 170 of Bid. |
计算分子量 | 22kDa |
成分 | Bid Antibody is supplied in PBS containing 0.02% sodium azide. |
纯化方式 | Bid Antibody is Ion exchange chromatography purified. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | 4℃可保存3个月,-20℃可保存1年。 |
背景资料 | Apoptosis plays a major role in normal organism development,tissue homeostasis,and removal of damaged cells.Disruption of this process has been implicated in a variety of diseases such as cancer.The Bcl-2 family of proteins is comprised of critical regulators of apoptosis that can be divided into two classes:those that inhibit apoptosis and those that promote cell death.Bid,a pro-apoptotic Bcl-2 family member,is cleaved by caspase-8 in response to apoptotic signals,exposing the Bcl-2 homology 3 (BH3) domain which is normally buried in the full-length protein.The cleaved complex is myris-toylated and translocated to the mitochondrial membrane where it may induce mitochondrial Bax and Bak to oligomerize. |
Uniprot ID | P55957 |
基因名全称 | BH3 interacting domain death agonist |
蛋白名全称 | BH3 interacting domain death agonist |
推荐稀释比 | Bid antibody can be used for detection of Bid by Western blot at 0.5 to 2μg/mL.Antibody can also be used for immunohistochemistry starting at 2μg/mL.For immunofluorescence start at 10μg/mL.Antibody validated:Western Blot in mouse samples;Immunohistochemistry in mouse samples and Immunofluorescence in mouse samples.All other applications and species not yet tested. |
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